Sunday, December 13, 2009

Recent literature on Adenoid Cystic Carcinoma

If you or someone you know experienced ACC and was treated at the Ohio State Medical Center, you might be anonymously mentioned in their recent article published in The Laryngoscope:

Patterns of recurrence and survival of head and neck adenoid cystic carcinoma after definitive resection. http://pubmed.gov/19877226 . (To get full text of this article, check with your local library listed here: http://www.nlm.nih.gov/medlineplus/libraries.html - interlibrary loan fees may apply. You can also pay for a one-day access fee to the publisher off of this page: http://www3.interscience.wiley.com/journal/122666245/abstract.)
The abstract of this article says that there was "no difference in survival, rate of recurrence, or time to recurrence" between patients that received radiation therapy and those that received surgery alone. Speaking with my taste-impaired tongue, I would really want to spare anyone else radiation therapy if there is no evident benefit in keeping the cancer at bay, but this research only looked at 57 people that received radiation, out of a total of 99 people. Too small a group, folks. What I would hope to see is someone to re-run this research on many tertiary care center records, and get some useful evidence to help guide the treatment protocols for my type of cancer.

Another recent article, in the journal Cancer E;pidemiology, Biomarkers & Prevention, describes incidence rates of cancers of the major salivary glands, including Adenoid Cystic Carcinoma: Incidence of Carcinoma of the Major Salivary Glands According to the WHO Classification, 1992 to 2006: A Population-Based Study in the United States. http://pubmed.gov/19861510 (You can get an interlibrary loan copy - may incur fees - from the libraries listed in the link above, or go directly to the publisher's site and pay for access: http://cebp.aacrjournals.org/content/18/11/2899.short ) I guess this one may include me, since my cancer was detected and reported in 2006.

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