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Saturday, May 25, 2013

Adenoid Cystic Carcinoma genome has been sequenced!!

Yes, I am pretty darn excited at this news!!

Memorial Sloan-Kettering Cancer Center has announced: 

Investigators Sequence the Genome of a Rare Head and Neck Cancer
http://www.mskcc.org/blog/investigators-sequence-genome-rare-head-and-neck

Their article about this was also just published - here is the PubMed link:
The mutational landscape of adenoid cystic carcinoma
http://www.ncbi.nlm.nih.gov/pubmed/23685749
(Remember, you can request a copy of the full-text of the article through your local public or medical library. Delivery fees may apply. Or, you can click on the publisher's link on the PubMed record and pay a higher price for full-text with a credit card. Since this study had NIH funding, the article will most likely be free to the public after a bit of time-say 6 to 12 months- has gone by.) 

Best sentence of their abstract comes at the end: "Collectively, our observations establish a molecular foundation for understanding and exploring new treatments for ACC."

In case you wonder if those donations you have been collecting or giving make a difference - here is the list of all the funding agencies behind this monumental research effort (so please, keep on giving and collecting!) (PS-links are mine, so you can get to see more about who is behind the research, and in the case of the ACCRF, get right to the donation page, so we can raise this work to the next level!):

This research was funded by the National Institutes of Health under grants RO1CA154767, R21DE023229, and 5T32CA009685; the Geoffrey Beene Foundation; the STARR Cancer Consortium; the Louis Gerstner Foundation; the American Head and Neck Society/American Academy of Otolaryngology — Head and Neck Surgery Foundation; the Howard Hughes Medical Institute Medical Research Fellows Program; and the Adenoid Cystic Carcinoma Research Foundation.

Update (5/29/13) NIDCR also had an announcement on this: http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB/May/adenoidcysticcarcinoma

3 comments:

Anonymous said...

Love it!!

Anonymous said...

Hi Teresa,

Yours is one of the MOST informative blogs on ACC among this confusing jungle of information online. Keep up the good work! I am battling ACC currently and finding how mercurial its behaviour is. It will be great to stay in touch. Is there an email address I could write to you on? It will be great to speak and learn from your experiences.

Warm regards,

Teresa Hartman said...

Thanks for the comments, both Anonymous-folks. You can get in touch with me through the Blogger profile on the lower right side of the page-my email is listed there, and I will put it here as well: teresa(dot)hartman(at)gmail(dot)com

Let me know if I can ever be of assistance, information-wise.

 
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